Survival was assessed every 3 months after the discontinuation of a study drug. Adverse events, laboratory values, and vital signs had been assessed regularly and graded according to the National Cancer Institute Common Terminology Criteria for Adverse Events, edition 4.0. End Points Main end points were progression-free survival and general survival . Secondary end factors included the target response rate , the duration of response , and basic safety.This is actually the fourth consecutive year that these minimally-invasive procedures have been ranked in the very best five. Reconstructive plastic surgery, which increases function and appearance to abnormal areas of the body, remained stable in 2005 relatively. The top five reconstructive methods were tumor removal , laceration repair , scar revision , hand surgery and breast reduction .
Stephan A. Grupp, M.D., Ph.D., Michael Kalos, Ph.D., David Barrett, M.D., Ph.D., Richard Aplenc, M.D., Ph.D., David L.