The most common symptoms of COPD are breathlessness , abnormal sputum , and a chronic cough. Daily activities, such as walking up a brief airline flight of stairs or carrying a suitcase, can become very difficult as the problem worsens gradually. There are significant unmet needs in the treating COPD including limited therapeutic options to improve lung function, decrease symptoms and control exacerbations.. Almirall strengthens its respiratory franchise with a new generation of Chronic Obstructive Pulmonary Disease treatment Almirall strengthens its position in the respiratory field with a positive advancement progress of another New Chemical substance Entity . This new course of inhaled long-acting bronchodilators is likely to provide additional symptom relief in patients living with COPD, and to form the basis of so called triple combinations together with ICS .The problem is the perverse incentive systems in scientific publishing. So long as authors are rewarded for publishing many articles and editors are rewarded for publishing them quickly, new ways of gaming the traditional publication versions will be invented more quickly than new control steps can be put in place.’ The article reports that ‘[p]oor building and development procedures conspire to create earthquakes more deadly than they want be. More people live in poverty in vulnerable buildings in crowded cities. That means that when the bottom shakes, the river breaches, or the tropical cyclone hits, more folks die.’ Just to illustrate is Haiti, where 220,000 people died after an earthquake in January.