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Median night-period spent with oxygen saturation significantly less than 90 % at 2,590 meters was 13 % vs. 57 %. The existing randomized, placebo-controlled, double-blind trial provides several novel results that are clinically relevant for individuals with OSA traveling to altitude. First, the data show that combined therapy with acetazolamide and autoCPAP provides a better oxygenation while asleep and wakefulness, prevents an exacerbation of rest apnea at altitude, and reduces the time spent awake during nights compared with autoCPAP alone. Second, the results demonstrate that autoCPAP only is an effective therapy for obstructive apneas/hypopneas even at altitude where central apneas/hypopneas emerge, the authors write.Aeras receives grant to develop new vaccines for TB TB vaccine development receives a boostThe Aeras Global TB Vaccine Base is pleased to announce that holland Ministry of Foreign Affairs has renewed its funding to Aeras with a pledge of yet another -11.7 million over four years to help expand its efforts to develop new vaccines to greatly help fight the global epidemic of tuberculosis. This expression of support represents a continuation in the long-position collaboration between your Dutch federal government, Aeras and its own research companions. This is the second grant to Aeras from the Netherlands Ministry of Foreign Affairs, representing a complete dedication of -30.4 million to Aeras since 2006.