The ACCORD Research Group: Effects of Mixture Lipid Therapy in Type 2 Diabetes Mellitus Patients with type 2 diabetes mellitus have got an increased incidence of atherosclerotic cardiovascular disease.1-4 This boost is attributable, in part, to associated risk elements, including dyslipidemia and hypertension Read more . The latter is seen as a elevated plasma triglyceride levels, low degrees of high-density lipoprotein cholesterol, and little, dense low-density lipoprotein particles.5,6 The Actions to Control Cardiovascular Risk in Diabetes study was designed to test the effect of intensive treatment of blood glucose and either blood circulation pressure or plasma lipids on cardiovascular outcomes in 10,251 sufferers with type 2 diabetes who have been at risky for cardiovascular disease.
Women contaminated with HIV-1 who became pregnant were described antenatal clinics for providers relating to the prevention of mother-to-child transmission, and the study medication was discontinued until a follow-up pregnancy test was harmful. Participants with HIV-1 disease who met national recommendations for the initiation of antiretroviral therapy through the follow-up period were described local HIV-1 clinics. Partners who were not contaminated with HIV-1 were interviewed on a quarterly basis about high-risk sexual methods and outward indications of sexually transmitted infections and underwent antibody assessment for HIV-1. The laboratory procedures have been described previously18 and are summarized in the Supplementary Appendix, available with the full text of the article at NEJM.org.